FLIRT

FMRIB's Linear Image Registration Tool

Overview

FLIRT is a very robust and accurate automated linear (affine) registration tool based around a multi-start, multi-resolution global optimisation method. It can be used for inter- and intra-modal registration with 2D or 3D images. In addition, it can be run with a number of different transformation models (degrees of freedom) and it implements a general cost function weighting scheme for all cost functions.

Papers

A paper on FLIRT has been published in Medical Image Analysis; see a related technical report (PS/PDF/HTML).
A further paper on FLIRT and MCFLIRT has been published in NeuroImage; see a related technical report (PS/PDF/HTML).
Alternatively, view a slideshow (PDF).

Software

FLIRT is available as part of the FMRIB Software Library.