Publications

2012

Trachtenberg AJ, Filippini N, Ebmeier KP, Smith SM, Karpe F, & Mackay CE. The effects of APOE on the functional architecture of the resting brain. Neuroimage. 2012 Jan 2;59(1):565-72

2011

Filippini N, Nickerson LD, Beckmann CF, Ebmeier KP, Frisoni GB, Matthews PM, Smith SM, Mackay CE. Age-related adaptations of brain function during a memory task are also present at rest. Neuroimage. 2011 Dec 1. [Epub ahead of print]

Lam M, Collinson SL, Sim K, Mackay CE, James AC, Crow TJ. Asymmetry of lexicon-semantic processing in schizophrenia changes with disease progression. Schizophr Res. 2011 Dec 2. [Epub ahead of print]

Sexton CE, Mackay CE, and Ebmeier KP. A Systematic Review and Meta-Analysis of Magnetic Resonance Imaging Studies in Late-Life Depression American Journal of Geriatric Psychiatry (in press)

Sexton CE, McDermott L, Kalu UG, Herrmann LL, Bradley KM, Allan CL, Le Masurier M, Mackay CE, Ebmeier KP. Exploring the pattern and neural correlates of neuropsychological impairment in late-life depression.Psychol Med. 2011 Oct 26:1-8. [Epub ahead of print]

Allan CL, Sexton CE, Kalu UG, McDermott LM, Kivimäki M, Singh-Manoux A, Mackay CE, Ebmeier KP. Does the Framingham Stroke Risk Profile predict white-matter changes in late-life depression? Int Psychogeriatr. 2011 Nov 17:1-8. [Epub ahead of print]

Suckling J, Barnes A, Job D, Brennan D, Lymer K, Dazzan P, Marques TR, Mackay C, McKie S, Williams SR, Williams SC, Deakin B, Lawrie S. The neuro/PsyGRID calibration experiment: Identifying sources of variance and bias in multicenter MRI studies. Hum Brain Mapp. 2011 Mar 21. [Epub ahead of print]

Trachtenberg AJ, Filippini N, Cheeseman J, Duff E, Neville MJ, Ebmeier KP, Karpe F & Mackay CE. The effects of APOE on brain activity do not simply reflect the risk of Alzheimer's disease Neurobiol Aging. 2011 Jan 11. [Epub ahead of print]

Heise V, Filippini N, Ebmeier KP, Mackay CE. The APOE ε4 allele modulates brain white matter integrity in healthy adults. Molecular Psychiatry 2011 Sep;16(9):908-16

Filippini N, Ebmeier KP, Beckmann CF, Frisoni GB, Smith SM, Matthews PM, Mackay CE. Differential effects of the APOE genotype on brain function across the lifespan. Neuroimage 2011 Jan 1;54(1):602-10

2010

KP Ebmeier, N Filippini and CE Mackay. Functional brain imaging and connectivity in dementia. In: DEMENTIA 4th Edition; Editors David Ames, Alistair Burns and John T. O’Brien, 2010, Hodder Education, London

Clark GM, Mackay CE, Davidson ME, Iversen SD, Collinson SL, James AC, Roberts N, Crow TJ. Paracingulate sulcus asymmetry; sex difference, correlation with semantic fluency and change over time in adolescent onset psychosis. Psychiatry Res. 2010 Oct 30;184(1):10-5.

Staudinger MR, Fink GR, Mackay CE & Lux. Gestalt perception and the decline of global precedence in older subjects. Cortex 2011 Jul-Aug;47(7):854-62

Filippini N, Douaud G, Mackay CE, Knight S, Talbot K & Turner MR. Corpus callosum involvement is a consistent feature of amyotrophic lateral sclerosis. Neurology. 2010 Nov 2;75(18):1645-52

Sexton CE, Mackay CE, Lonie JA, Bastin ME, Terriere E, O’Carroll RE, Ebmeier KP. MRI correlates of episodic memory in Alzheimer’s disease, MCI and healthy aging.  Psychiatry Research: Neuroimaging 2010 Oct 30;184(1):57-62

Sexton CE, Kalu UG, Filippini N, Mackay CE, Ebmeier KP. A meta-analysis of diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease. Neurobiol Aging. 2010 Jul 7. [Epub ahead of print]

Murphy SE & Mackay CE.Using MRI to measure drug action: caveats and new directions. J Psychopharmacol. 2010 Jun 28. [Epub ahead of print]

Trachtenberg AJ, Filippini N, Mackay CE. The effects of APOE-ε4 on the BOLD response. Neurobiology of Aging 2010 (in press)

C.E. Mackay, E. Roddick, T.R. Barrick, N. Roberts, T.J. Crow, A.J. Lloyd, A.H. Young, N. Ferrier. Sex differences in lobe volumes in bipolar disorder. Bipolar Disorders 2010 May;12(3):306-11

G.M. Clark, T.R. Barrick, S.L. Collinson, A.C. James, N. Roberts, T.J. Crow and C.E. Mackay. Loss of Planum Temporale asymmetry but not cerebral torque in adolescent onset psychosis. Schizophrenia Research 2010 Jul;120(1-3):84-6

Suckling J, Barnes A, Job D, Brenan D, Lymer K, Dazzan P, Marques TR, Mackay C, McKie S, Williams SR, Williams SC, Lawrie S, Deakin B. Power calculations for multicenter imaging studies controlled by the false discovery rate. Human Brain Mapping (in press)

Klein JC, Rushworth MF, Behrens TE, Mackay CE, de Crespigny AJ, D'Arceuil H, Johansen-Berg H. Topography of connections between human prefrontal cortex and mediodorsal thalamus studied with diffusion tractography Neuroimage. 2010 Mar 3. [Epub ahead of print]

Biswal BB, Mennes M, Zuo XN, Gohel S, Kelly C, Smith SM, Beckmann CF, Adelstein JS, Buckner RL, Colcombe S, Dogonowski AM, Ernst M, Fair D, Hampson M, Hoptman MJ, Hyde JS, Kiviniemi VJ, Kötter R, Li SJ, Lin CP, Lowe MJ, Mackay C, Madden DJ, Madsen KH, Margulies DS, Mayberg HS, McMahon K, Monk CS, Mostofsky SH, Nagel BJ, Pekar JJ, Peltier SJ, Petersen SE, Riedl V, Rombouts SA, Rypma B, Schlaggar BL, Schmidt S, Seidler RD, Siegle GJ, Sorg C, Teng GJ, Veijola J, Villringer A, Walter M, Wang L, Weng XC, Whitfield-Gabrieli S, Williamson P, Windischberger C, Zang YF, Zhang HY, Castellanos FX, Milham MP. Toward discovery science of human brain function. Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4734-9

BJ MacIntosh, N Filippini, MA Chappell, MW Woolrich, CE Mackay, P Jezzard. Assessment of arterial arrival times derived from multiple inversion time pulsed arterial spin labelling MRI. Magnetic Resonance in Medicine 2010, 63(3):641-7

2009

Smith SM, Fox PT, Miller KL, Glahn DC, Fox PM, Mackay CE, Filippini N, Watkins KE, Toro R, Laird AR, Beckmann CF. Correspondence of the brain's functional architecture during activation and rest. Proc Natl Acad Sci U S A. 2009 106(31):13040-5

Sexton CE, Mackay CE, Ebmeier KP. A Systematic Review of Diffusion Tensor Imaging Studies in Affective Disorders.  Biol Psychiatry. 2009 66(9): 814-823

Douaud G, Mackay C, Andersson J, James S, Quested D, Ray MK, Connell J, Roberts N, Crow TJ, Matthews PM, Smith S, James A Schizophrenia delays and alters maturation of the brain in adolescence. Brain. 2009, 132(Pt 9):2437-48

Filippini N, Zarei M, Beckmann CF, Galluzzi S, Borsci G, Testa C, Bonetti M, Beltramello A, Ghidoni R, Benussi L, Binetti G, Frisoni GB. Regional atrophy of transcallosal prefrontal connections in cognitively normal APOE epsilon4 carriers. J Magn Reson Imaging. 2009 May;29(5):1021-6.

Filippini N, McIntosh BJ, Bhomra A, Hough MG, Ebmeier K, Goodwin GM, Frisoni GB, Flint J, Smith S, Matthews PM, Mackay CE. Distinct patterns of brain activity in young adults carrying the APOE-ε4 allele Proc Nat Acad Sci USA Apr 28;106(17):7209-14 

Collinson SL, Mackay CE, O J, James AC, Crow TJ Dichotic listening impairments in early onset schizophrenia are associated with reduced left temporal lobe volume. Schizophr Res. 2009 Jul;112(1-3):24-31

Rezaie R, Daly EM, Cutter WJ, Murphy DG, Robertson DM, Delisi LE, Mackay CE, Barrick TR, Crow TJ, Roberts N. (2009) The influence of sex chromosome aneuploidy on brain asymmetry. Am J Med Genet B Neuropsychiatr Genet. 5:150B(1):74-85

Filippini N, Rao A, Wetten S, Gibson RA, Borrie M, Guzman D, Kertesz A, Loy-English I, Williams J, Nichols T, Whitcher B, Matthews PM. Anatomically-distinct genetic associations of APOE epsilon4 allele load with regional cortical atrophy in Alzheimer's disease. Neuroimage. 2009 Feb 1;44(3):724-8.

2008

Holmes NP, Spence C, Hansen, PC, Mackay CE, Calvert GA (2008). The multisensory attentional consequences of tool-use: An fMRI study. PLoS ONE, 3(10):e3502.

D. Arnone, T.R. Barrick, S. Chengappa, C.E. Mackay, C.A. Clark and M.T. Abou-Saleh. Corpus callosum damage in heavy marijuana use: preliminary evidence from diffusion tensor tractography and tract-based spatial statistics. Neuroimage 2008 Jul 1;41(3):1067-74

S. Lux, S. Keller, C.E. Mackay, G. Ebers, J.C. Marshall, L. Cherkas, R. Rezaie, N. Roberts, G.R. Fink, J.M. Gurd. Crossed cerebral lateralization for verbal and visuo-spatial function in a pair of handedness discordant monozygotic twins: MRI and fMRI brain imaging. J Anat. 2008; 212(3):235-48.

Norbury R, Mackay CE, Cowen PJ, Goodwin GM, Harmer CJ. The effects of reboxetine on emotional processing in healthy volunteers: an fMRI study. Mol Psychiatry. 2008; 13(11):1011-20

Kar Ray M, Mackay CE, Harmer CJ, Crow TJ. Bilateral Generic Working Memory Circuit Requires Left-Lateralized Addition for Verbal Processing. Cereb Cortex. 2008; 18(6):1421-8

2007

Norbury R, Mackay CE, Cowen PJ, Goodwin GM, Harmer CJ. Short-term antidepressant treatment and facial processing. Functional magnetic resonance imaging study.Br J Psychiatry. 2007 Jun;190:531-2

Klein JC, Behrens TE, Robson MD, Mackay CE, Higham DJ, Johansen-Berg H. Connectivity-based parcellation of human cortex using diffusion MRI: Establishing reproducibility, validity and observer independence in BA 44/45 and SMA/pre-SMA. Neuroimage. 2007 Jan 1;34(1):204-11

2006

Filippini N, Scassellati C, Boccardi M, Pievani M, Testa C, Bocchio-Chiavetto L, Frisoni GB, Gennarelli M. Influence of serotonin receptor 2A His452Tyr polymorphism on brain temporal structures: a volumetric MR study. Eur J Hum Genet. 2006 Apr;14(4):443-9.

Heiervang E, Behrens TE, Mackay CE, Robson MD, Johansen-Berg H. Between session reproducibility and between subject variability of diffusion MR and tractography measures.Neuroimage. 2006 Nov 15;33(3):867-77
T.R. Barrick, N. Lawes, C.E. Mackay and C.A. Clark. Temporal-parietal and temporal-frontal white matter pathway asymmetry demonstrated by diffusion tensor tractography. Cerebral Cortex 2006; 17(3):591-8

Geddes J, Mackay C, Lloyd S, Simpson A, Power D, Russell D, Jirotka M, Katzarova M, Rossor M, Fox N, Fletcher J, Hill D, McLeish K, Chen Y, Hajnal JV, Lawrie S, Job D, McIntosh A, Wardlaw J, Sandercock P, Palmer J, Perry D, Procter R, Ure J, Hartswood M, Slack R, Voss A, Ho K, Bath P, Clarke W, Watson G. Designing for e-Health: Recurring Scenarios in Developing Grid-based Medical Imaging Systems. Stud Health Technol Inform. 2006; 120: 336-47

S.M. Smith, M. Jenkinson, H. Johansen-Berg, D. Rueckert, T.E. Nichols, C.E. Mackay, K.E. Watkins, O. Ciccarelli, M.Z. Cader, P.M. Matthews and T.E.J. Behrens. Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data. Neuroimage 2006; 31(4): 1487-505

C.J. Harmer, C.E. Mackay, C.B. Reid, P.J. Cowen, G.M. Goodwin. Antidepressant drug treatment modifies the neural processing of non-conscious threat cues. Biological Psychiatry 2006; 59(9): 816-820

2005

R. Honea, T.J. Crow, D. Passingham & C.E. Mackay.  Regional decreases in brain volume in schizophrenia: a meta-analysis of voxel based morphometry studies. American Journal of Psychiatry 2005;162: 2233-2245

T.R. Barrick, C.E. Mackay, S. Prima, F. Maes, D.Vandermeulen, T.J Crow, and N Roberts. Automatic analysis of cerebral asymmetry: an exloratory study of the relationship between brain torque and planum temporale asymmetry. Neuroimage 2005, 24(3): 678-91

2004

R.D. Rogers, N. Ramnani, C.E. Mackay, J Wilson, P. Jezzard, C.S. Carter, and S.M. Smith. Distinct portions of the anterior cingulate and medial prefrontal cortex are activated by reward processing in separable phases of decision-making cognition. Biological Psychiatry 2004, 55: 594-602

2003

C.E. Mackay, T.R. Barrick, N.Roberts, L.E. DeLisi, F. Maes, D.Vandermeulen and T.J Crow. Application of a new image analysis technique to the study of brain asymmetry in schizophrenia. Psychiatry Research; Neuroimaging 2003, 124 (1): 25-35

S.L. Collinson, C.E. Mackay, A. James, N. Roberts, T. Phillips and T.J. Crow.  Brain volume, asymmetry and intellectual impairment in early onset schizophrenia. British Journal of Psychiatry. 2003 183: 114-120

CE Mackay's miscellaneous older papers:

U.C. Wieshmann, C.E. Denby, P.R. Eldridge, N. Roberts N, C.E. Mackay, J.A. Webb, B.M. Tedman, D.W. Chadwick, D.F. Smith. Foramen ovale recordings: A presurgical investigation in epilepsy. European Neurology 2003, 49 (1): 3-7

M. Garcia-Finana, L. M. Cruz-Orive, C. E. Mackay, B. Pakkenberg and N. Roberts.  Comparison of MR imaging against physical sectioning to estimate the volume of human cerebral compartments. Neuroimage, 2003, 18: 505-516

S.S. Keller, U.C. Wieshmann, C.E. Mackay, C.E. Denby, N. Roberts. Voxel based morphometry of grey matter abnormalities in patients with medically intractable temporal lobe epilepsy: effects of side of seizure onset and epilepsy duration. Journal of Neurology, Neurosurgery and Psychiatry 2002, 73: 648-656

S.S. Keller, C.E. Mackay, T.R. Barrick, U.C. Wieshmann, M.A. Howard and N. Roberts. Voxel-based morphometric comparison of hippocampal and extrahippocampal abnormalities in patients with left and right hippocampal atrophy. Neuroimage 2002, 16 (1):23-31

J.J. Downes, C.E. Mackay, D. Tsivilis, A.R. Mayes, K.D. Singh, & N. Roberts. Prefrontal cortical activation during word associative, face associative, and word-face associative encoding. Brain and Cognition, 2001, 47:69-72

C.E. Mackay, J.A. Webb, P.R. Eldridge, N. Roberts, D.W. Chadwick and G.H. Whitehouse. Quantitative magnetic resonance imaging in the pre-surgical evaluation of patients with temporal lobe epilepsiy. Magnetic Resonance Imaging, 2000, 18:1187-1199

C.E. Mackay , N. Roberts, L. Steffensen and B. Pakkenberg. Comparison of compartment volumes estimated from MR images and physical sections of formalin fixed cerebral hemispheres. Acta Stereologica, 1999; 18 (2): 149-159

C.E. Mackay , N. Roberts, A. Mayes , J.J. Downes , J.K. Foster,  D. Mann & R.H.T. Edwards. An exploratory study of the relationship between face recognition memory and the volume of medial temporal lobe structures in healthy young males. Behavioural Neurology, 1998, 11; 3-21.