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J Scholz, MC Klein, TE Behrens, and H Johansen-Berg (2009)

Training induces changes in white-matter architecture

Nat Neurosci 12(11):1370-1371.

Although experience-dependent structural changes have been found in adult gray matter, there is little evidence for such changes in white matter. Using diffusion imaging, we detected a localized increase in fractional anisotropy, a measure of microstructure, in white matter underlying the intraparietal sulcus following training of a complex visuo-motor skill. This provides, to the best of our knowledge, the first evidence for training-related changes in white-matter structure in the healthy human adult brain.